Potential Company Opportunities

Do you want to start a new company? OTL has identified new technologies well-positioned to form the basis of startup companies.  When such a technology becomes available for licensing, we post it to the list below. These Potential Company Opportunities represent only a small fraction of the technologies available for licensing from the University of Florida. Contact a licensing officer in your area of interest to discuss other opportunities that might be available.

  • Fibroblast Growth Factor Receptor Peptoid Agonists for Wound Healing

    15992 - These peptoid ligands provide more stability and cost efficiency than their peptide counterparts and act as fibroblast growth factor receptor agonists for treatment of wounds specifically after radiation treatments. Recently, the medicinal chemistry field has taken great interest in fibroblast growth factor receptors (FGFRs) targeting drugs. Fibroblast growth factors (FGFs) bind to ... Read more

  • Portable Device that Helps Stroke, Alzheimer's and Parkinson's Patients Swallow and Cough Safely

    14739 - This noninvasive, portable electronic device treats swallowing and coughing difficulties in patients with impaired airway protection. Impaired airway protection is a common symptom of neurologic and neurodegenerative conditions such as stroke, multiple sclerosis, amyotrophic lateral sclerosis (Lou Gehrig’s disease), Alzheimer’s disease and Parkinson’s disease. The ... Read more

  • Low-Pressure, Windowless Solar Thermochemical Reactor for Large-Scale Fuel Production

    16603 - This solar thermochemical reactor allows for large scale deployment by revolutionizing solar thermochemical fuel production and overcoming challenges within the industry. Producing fuel by converting solar energy into chemical energy via a reactor tackles the world’s expanding energy needs, reduces greenhouse gas emissions, and is a potentially viable option for the efficient,... Read more

  • Functionalized Fullerenes for Energy Efficient Laser Ignition Applications

    16531 - These functionalized fullerenes can be ignited with low-intensity lasers, allowing uniform coating on explosives for homogeneous or multi-point ignition. Many industrial processes require ignition to start chemical conversions, and electric spark and laser are the most popular. Electric spark ignition requires input from high-voltage sources, which can be affected by stray electromagn... Read more

  • Reverse Osmosis Membrane System for Treating Landfill Leachate at Lower Cost

    16476 - This landfill leachate system includes disposable reverse osmosis membranes that process the liquid run-off from dump sites. The membranes are less expensive and easier to use than other effluent filters. Until now, strict environmental regulations have made leachate treatments costly and difficult for landfill operators to manage. Researchers at the University of Florida have develope... Read more

  • Low-Pressure, Windowless Solar Thermochemical Reactor for Large-Scale Fuel Production

    13911 - This solar thermochemical reactor allows for large scale deployment by revolutionizing solar thermochemical fuel production and overcoming challenges within the industry. Producing fuel by converting solar energy into chemical energy via a reactor tackles the world’s expanding energy needs, reduces greenhouse gas emissions, and is a potentially viable option for the efficient,... Read more

  • Device for Treating Bleeding Esophageal Varices

    15347 - This inflating and deflating balloon tamponade is used to stabilize bleeding esophageal varices in critical patients. Esophageal varices are abnormal, enlarged veins in the esophagus that can leak blood and possibly rupture. They occur most often in people with serious liver diseases and conditions like hepatitis and chronic alcoholism. Twelve million Americans have been infected wi... Read more

  • Magnetically-Triggered Drug Delivery Vehicles for Controlled, Targeted Therapy

    14866 - This magnetically-triggered drug delivery platform can deliver a wide array of nano-medicines to targeted cells in the body. Nanotechnology is a growing science that is useful in targeting and treating cancerous cells and other harmful agents. The global market for nanoparticles in life sciences is estimated at over $30 billion. While a variety of available nano-medicines allow for... Read more

  • Software App that Assesses Quality of Cancer Treatment Programs in Real Time

    13838 - This software application electronically tracks in real time the quality of management received by a patient within a multidisciplinary breast cancer program for the purposes of achieving National Breast Cancer Program Accreditation. Typically, breast cancer programs analyze hundreds of charts to measure the quality of the care they give, comparing themselves to national metrics in ... Read more

  • Self-Healing Polymers with Shape Recovery

    16276 - These self-healing polymers spontaneously mend wear-related fissures and cracks to increase the lifespan of many different products, including components for airplanes and spacecraft. Traditionally, when an item such as a machined component showed signs of wear-and-tear, a human fixed or replaced it. Today’s designers are working to reduce the need for hands-on repairs. Researc... Read more

  • Nutritional Supplement for Weight Management and Digestive Health

    13671 - This nutritional supplement is able to suppress appetite and helps with weight loss. About one-third of U.S. adults are obese, according to the Centers for Disease Control and Prevention. In 2010, no state had less than 20 percent prevalence of obesity. More than 65 percent of the world’s population lives in countries where overweight and obesity kill more people than being u... Read more

  • Anticancer Agents to Inhibit Cancer Cell Growth

    15128 - This first-in-class compound inhibits cancer cell proliferation. The Epidermal Growth Factor Receptor (EGFR) family members – EGFR, Human Epidermal Growth Factor Receptor-2 (HER2) and Human Epidermal Growth Factor Receptor-3 (HER3) – are well established as proto-oncogenes that play key roles in the initiation and progression of a number of human cancers, including breas... Read more

  • Certain Green Algae Extracts that Potentially Prevent Cancer and Other Diseases

    14452 - Specific green algae extracts that mitigate damage caused by oxidative and inflammatory stress that otherwise could lead to cellular damage, inflammation and cancer by activating the body’s antioxidant response element. Seaweed extracts have been used in medicine for many centuries; consumption of green, red and brown algae is inversely related to various cancers. Laboratory stu... Read more

  • Aminoacyl Sulfamide Compounds that Inhibit Cancerous Cell Growth and Virus Spreading

    15791 - This series of chemical compounds reduce the spread of cancerous cells and viruses, by suppressing their ability to synthesize proteins and replicate viruses. Transfer RNA (tRNA) and messenger RNA (mRNA) are important for the replication and spread of cancerous cells. Aminoacyl sulfamides, which are stable compounds structurally mimicking cognate intermediates, can be high-affinity ... Read more

  • Therapeutic Compounds to Enhance Cognition, Counteract Depression and Treat Smoking Addiction

    13337 - These compounds enable effective treatment of neurological disorders involving cognitive deficits (including Alzheimer’s and Parkinson’s diseases), depression and drug dependences such as tobacco (nicotine) and betel nut addictions. Neurological diseases including drug addictions are a major health cost to human societies. By 2030, more than 8 million individuals will di... Read more

  • Halogenated Phenazines: Antibacterial Compounds that Prevent and Eradicate Microbial Biofilms

    14887 - This series of antibacterial agents, known as the halogenated phenazines, are able to eradicate free-floating (planktonic) bacteria in addition to persistent, surface-attached bacterial biofilms against gram positive organisms such as methicillin-resistant Staphylococcus aureus (MRSA), methicillin-resistant Staphylococcus epidermidis (MRSE) and vancomycin-resistant Enterococcus faec... Read more

  • Computer-Guided Orthodontic Tools for Optimal and Efficient Placement of Braces

    15180 - This computer-guided bracket positioning device and indexing tool employs tracking sensors for more precise, efficient, and effective orthodontic bracket placement. In the United States alone, more than 4 million people wear braces. These patients invest thousands of dollars into orthodontic procedures to align their smiles and prevent complications due to crooked teeth or misaligne... Read more

  • Nerve Stimulator Therapy Offers Relief for Neurological Disorders

    15256 - This closed-loop neural prosthesis offers therapy for individuals suffering from conditions such as anxiety, chronic pain, sleep disorders, epilepsy, and post-traumatic stress disorder. An estimated 70 million adults in the United States suffer from at least one of these disorders. Available treatments for these diseases include pharmaceutical therapy, surgery, psychotherapy, and li... Read more

  • Multipurpose Optical Tracking System for Safe and High-Precision Radiotherapy

    14057 - This multipurpose optical tracking system potentially improves the safety and accuracy of advanced radiotherapy. The global radiotherapy market will have a value of $8.1 billion by 2019. Radiotherapy uses high-energy particles emitted from a linear accelerator to destroy tumors. To reap the benefit of high-precision radiotherapy, the patient has to be precisely positioned or healthy... Read more

  • Magnetically-Aligned Nerve Guide Scaffold for Safe, Comprehensive Peripheral Nerve Regeneration

    15266 - This magnetically aligned tissue engineering scaffold potentially enables nerve regeneration in missing nerve gaps over two centimeters long. In humans, the peripheral nerves connect the brain and spinal cord to the rest of the body. The side effects of cut nerves can include loss of feeling in limbs and sharp pain. Today, the nerve repair market in the United States is about $1.3-$... Read more

  • Optical Device to Protect Privacy in 3D Time-of-Flight (TOF) Cameras

    15360 - These privacy-preserving optics filter or modulate light before it reaches the sensor of time-of-flight cameras, preserving the privacy of subjects seen on live camera feeds and recordings without impacting depth quality. The video surveillance, gesture recognition and depth sensing market size in total is expected to exceed $25 billion by 2016. Surveillance of the public is ever-in... Read more

  • Absorption-Based Heater for More Efficient Residential Water Heating

    14697 - This absorption-based heater design uses a flow loop to capture low grade heat for heating and cooling purposes at higher efficiency for residential water heating. Ultra-thin absorbers and desorbers and the manner in which the process fluid is pumped achieve high heat exchange efficiency in this compact machine. Due to their large size, absorption-based heaters have been the domain ... Read more

  • Sinkhole Detection that Uses Seismic Waves to Determine Subterranean Conditions

    13667 - This method and device for sinkhole detection uses multiple waveform spectrums to characterize various subterranean properties that contribute to sinkhole formation, without using boring or other intrusive tests. Sinkholes occur worldwide and can cause millions of dollars in property damage as well as endanger human lives. Subsurface conditions such as voids in rock, pockets of air,... Read more

  • Precursor Molecules for Thin-Film Diffusion Barriers that Prevent Electrical Shorts in Integrated Circuits

    15475 - These tungsten nitrido precursor molecules are starting materials for low-temperature deposition of tungsten carbonitride (WNCx) thin films that serve as diffusion barriers that prevent electrical shorts in integrated circuits. A common example is prevention of Cu diffusion into other areas within an integrated circuit that uses Cu in its metallization scheme. Virtually all modern cons... Read more

  • Simulated Surgeries Using 3-D Models and Visual Feedback Software

    14746 - These mixed-reality simulators, which include 3-D models of body parts and real-time visual feedback software, allow medical residents to practice surgical techniques before operating on real patients. The 3-D printed models are constructed from scans of actual patients’ brains, spines, or other body parts, and are synched with corresponding virtual fluoroscopy images in the s... Read more