{"id":319,"date":"2020-04-12T14:46:49","date_gmt":"2020-04-12T14:46:49","guid":{"rendered":"https:\/\/research.ufl.edu\/rcr\/?page_id=319"},"modified":"2026-03-09T15:32:31","modified_gmt":"2026-03-09T15:32:31","slug":"rigor-reproducibility","status":"publish","type":"page","link":"https:\/\/research.ufl.edu\/rcr\/rigor-reproducibility\/","title":{"rendered":"Rigor &amp; Reproducibility"},"content":{"rendered":"\n<p>There has been a growing awareness in recent years that some of the research literature is not reproducible.  It is particularly important in biomedical research that preclinical studies are rigorously designed and reproducible, and the National Institutes of Health (NIH) are therefore placing increasing emphasis on enhancing reproducibility through rigor and  transparency in <a aria-label=\"NIH-funded research and research training (opens in a new tab)\" href=\"https:\/\/grants.nih.gov\/policy\/reproducibility\/guidance.htm\" target=\"_blank\" rel=\"noreferrer noopener\">NIH-funded research and research training<\/a>.  Resources for training in rigor and reproducibility are included in this website along with RCR materials.  <\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity is-style-wide\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">Rigor and Reproducibility Seminar Series<\/h2>\n\n\n\n<p>This seminar series is jointly hosted by the&nbsp;<a href=\"https:\/\/movementdisorders.ufhealth.org\/\" target=\"_blank\" rel=\"noreferrer noopener\">UF Movement Disorders and Neurorestoration Program<\/a>&nbsp;and the&nbsp;<a href=\"https:\/\/library.health.ufl.edu\/\" target=\"_blank\" rel=\"noreferrer noopener\">UF Health Science Center Libraries<\/a>. Hear from leading&nbsp;<a href=\"https:\/\/uf-repro.github.io\/movementdisorders-seminar\/\" target=\"_blank\" rel=\"noreferrer noopener\">national and international experts<\/a>&nbsp;on rigor and reproducibility topics.&nbsp; To register, please use the links in the&nbsp;<a href=\"https:\/\/uf-repro.github.io\/movementdisorders-seminar\/\" target=\"_blank\" rel=\"noreferrer noopener\">seminar schedule<\/a>, after which you will receive information about joining the zoom meeting and participating in Q&amp;A discussions.&nbsp;&nbsp;This program and seminar series is funded by the National Institute of Neurological Disorders and Stroke (NINDS) through&nbsp;<a href=\"https:\/\/grantome.com\/grant\/NIH\/T32-NS082168-05\">T32 NS082128<\/a>, awarded to PIs Dawn Bowers (College of Public Health &amp; Health Professions) and David E. Vaillancourt (College of Health &amp; Human Performance).<\/p>\n\n\n\n<p>Recordings for past talks in this series can be found at&nbsp;<a href=\"https:\/\/uf-repro.github.io\/movementdisorders-seminar\/\">https:\/\/uf-repro.github.io\/movementdisorders-seminar\/<\/a>&nbsp;<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity is-style-wide\"\/>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"resources-from-uf-libraries\">Resources from UF Libraries<\/h2>\n\n\n\n<p>You can find a great list of resources and a calendar of upcoming HSCL workshops at the&nbsp;<a rel=\"noreferrer noopener\" href=\"https:\/\/guides.uflib.ufl.edu\/reproducibility\/lessons\" target=\"_blank\">Research Reproducibility and Open Science library guide<\/a>.<\/p>\n\n\n\n<p>The&nbsp;<a rel=\"noreferrer noopener\" href=\"https:\/\/arcs.uflib.ufl.edu\/consultations\/\" target=\"_blank\">Academic Research Consulting &amp;&nbsp;Services (ARCS)<\/a>&nbsp;group at the UF library, offers free consultation and service about a variety of relevant topics, including AI, data management, bioinformatics, high performance computing, reproducibility, and research integrity.<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity is-style-wide\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">Scientific Rigor<\/h2>\n\n\n\n<figure class=\"wp-block-image alignright size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"630\" height=\"497\" src=\"https:\/\/research.ufl.edu\/rcr\/wp-content\/uploads\/image.png\" alt=\"\" class=\"wp-image-340\" style=\"width:213px;height:168px\" srcset=\"https:\/\/research.ufl.edu\/rcr\/wp-content\/uploads\/image.png 630w, https:\/\/research.ufl.edu\/rcr\/wp-content\/uploads\/image-300x237.png 300w\" sizes=\"auto, (max-width: 630px) 100vw, 630px\" \/><\/figure>\n\n\n\n<p>Scientific rigor is <a rel=\"noreferrer noopener\" aria-label=\"defined by the NIH (opens in a new tab)\" href=\"https:\/\/grants.nih.gov\/policy\/reproducibility\/index.htm\" target=\"_blank\">defined by the NIH<\/a> as the &#8220;strict application of the scientific method to ensure unbiased and well-controlled experimental design, methodology, analysis, interpretation and reporting of results.&#8221;&nbsp; The application of rigor ensures robust and unbiased experimental design, methodology, analysis, interpretation, and reporting of results. When a result can be reproduced by multiple scientists, it validates the original results and readiness to progress to the next phase of research. This is especially important for clinical trials in humans, which are built on studies that have demonstrated a particular effect or outcome.<\/p>\n\n\n\n<p>NIH Infographic: <a aria-label=\"Enhancing Reproducibility in NIH Applications Resource Chart (opens in a new tab)\" href=\"https:\/\/grants.nih.gov\/grants\/Rigor-and-Reproducibility-Chart-508.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">Enhancing Reproducibility in NIH Applications Resource Chart<\/a><\/p>\n\n\n\n<p>See the <a aria-label=\"Rigor &amp; Reproducibility Resources\" href=\"https:\/\/research.ufl.edu\/rcr\/resources\/rigor-reproducibility\/\" target=\"_blank\" rel=\"noreferrer noopener\">Rigor &amp; Reproducibility resources<\/a> and <a href=\"https:\/\/grants.nih.gov\/policy-and-compliance\/policy-topics\/reproducibility\/training\" target=\"_blank\" rel=\"noreferrer noopener\">Rigor &amp; Reproducibility training<\/a> web pages for more information. See also the NINDS webpage for &#8220;<a href=\"https:\/\/www.ninds.nih.gov\/Current-Research\/Trans-Agency-Activities\/Rigor-Transparency\/RigorChampionsAndResources\" target=\"_blank\" rel=\"noreferrer noopener\">Rigor Champions and Resources<\/a>&#8220;.<\/p>\n\n\n\n<p><strong>NIH requirements for rigor &amp; reproducibility training<\/strong> are detailed in NIH notice <a rel=\"noreferrer noopener\" href=\"https:\/\/grants.nih.gov\/grants\/guide\/notice-files\/NOT-OD-20-033.html\" target=\"_blank\">NOT-OD-20-033<\/a> and <a rel=\"noreferrer noopener\" href=\"https:\/\/grants.nih.gov\/grants\/guide\/notice-files\/NOT-OD-20-090.html\" target=\"_blank\">NOT-OD-090<\/a>, and summarized below. A recommended plan for training in rigor &amp; reproducibility is available at the <a rel=\"noreferrer noopener\" href=\"https:\/\/www.ctsi.ufl.edu\/education\/grant-workshops\/nih-training-programs-at-the-university-of-florida\/training-grant-toolkit\/\" target=\"_blank\">Training Grant Toolkit<\/a>.<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><th>Type of Application<\/th><th>Changes<\/th><\/tr><tr><th>Institutional Research Training (T)<br>and<br>Institutional Career Development (K)<\/th><td>The Program Plan section of the application will be expected to include a description of how the program and faculty will provide training in rigorous research design and relevant data science and quantitative approaches. There is a new requirement to include a Plan for Instruction in Methods for Enhancing Reproducibility attachment.<\/td><\/tr><tr><th>Individual Fellowships (F)<\/th><td>In describing their training goals and objectives in the Program Plan attachment, fellowship candidates will be expected to address, as applicable, any new research skills they plan to acquire in the areas of rigorous research design, experimental methods, quantitative approaches, and data analysis and interpretation. In the Research Strategy section of the Program Plan attachment, fellowship candidates will be expected to describe (a) the strengths and weaknesses in the rigor of the prior research that serves as the key support for the proposed project, (b) plans to address any weaknesses in the rigor of the prior research, (c) how the experimental objectives proposed will achieve robust and unbiased results, and (d) how relevant biological variables are factored into research designs and analyses. If applicable, fellowship candidates will be required to include the Authentication of Key Biological and\/or Chemical Resources attachment.<\/td><\/tr><tr><th>Individual Career Development (K)<\/th><td>In describing their career development plans in the Program Plan attachment, candidates for career development awards will be expected to address, as applicable, any new research skills they plan to acquire in the areas of rigorous research design, experimental methods, quantitative approaches, and data analysis and interpretation.<\/td><\/tr><\/tbody><\/table><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>There has been a growing awareness in recent years that some of the research literature is not reproducible. It is particularly important in biomedical research that preclinical studies are rigorously designed and reproducible, and the National Institutes of Health (NIH) are therefore placing increasing emphasis on enhancing reproducibility through rigor and transparency in NIH-funded research [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"parent":0,"menu_order":7,"comment_status":"closed","ping_status":"closed","template":"page-templates\/page-sidebar-navigation.php","meta":{"featured_post":"","footnotes":""},"class_list":["post-319","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/research.ufl.edu\/rcr\/wp-json\/wp\/v2\/pages\/319","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/research.ufl.edu\/rcr\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/research.ufl.edu\/rcr\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/research.ufl.edu\/rcr\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/research.ufl.edu\/rcr\/wp-json\/wp\/v2\/comments?post=319"}],"version-history":[{"count":23,"href":"https:\/\/research.ufl.edu\/rcr\/wp-json\/wp\/v2\/pages\/319\/revisions"}],"predecessor-version":[{"id":1505,"href":"https:\/\/research.ufl.edu\/rcr\/wp-json\/wp\/v2\/pages\/319\/revisions\/1505"}],"wp:attachment":[{"href":"https:\/\/research.ufl.edu\/rcr\/wp-json\/wp\/v2\/media?parent=319"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}