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Startups in the News

  • AxoGen CEO Karen Zaderej Named A Florida Entrepreneur of the Year (BioSpace)
    As a female chief executive officer in the healthcare industry CEO Karen Zaderej often stands out in a male-dominated industry. This month she stood out for another reason – as the Ernst & Young Entrepreneur of the Year 2018 Award winner for the state of Florida in the healthcare category. Zaderej leads AxoGen, a UF startup and UF Innovate | Sid Martin Biotech graduate. She said she typically stands out as the lone woman in a group shot of her peers. Even among the other entrepreneur winners in additional categories, she remained the lone female for Florida. She noted that there is still a glass ceiling that “limits the opportunity” for women to be fully recognized and contribute as capable leaders. However, Zaderej noted some investors are “putting their money where their mouths are” in order to promote diversity at the C-suite level and on boards of directors.... Read more »
  • ViewRay MRI Guides Brachytherapy Planning (PhysicsWorld)
    A team of clinicians at the University of Wisconsin have used a ViewRay MRI-guided radiotherapy system to perform brachytherapy planning for cervical cancer. So, what motivated the team to use the UF startup’s system to perform brachytherapy planning? And how does use of the system fit time-wise alongside its use for treatments? Writing in the journal Brachytherapy, the authors present the results of some 142 fractions of intracavitary brachytherapy, performed between April 2015 and January 2017 on 29 cervical cancer patients – the first ever clinical use of ViewRay-guided brachytherapy (Brachytherapy 10.1016/j.brachy.2018.04.005). They conclude that “time to treatment using this approach was shorter compared to diagnostic MRI” and that the ViewRay system also provided “significant advantage in visualizing the tumour and cervix compared to CT.”... Read more »
  • Exactech Earns Research Award at International Computer-Assisted Surgery Conference for ExactechGPS® Knee Application (BusinessWire)
    UF startup Exactech, a leading developer and producer of bone and joint restoration products and biologic solutions for extremities, knee and hip, earned the Second Place Best Clinical Podium Presentation Award for one of five new research studies presented on the company’s latest computer guidance technology for knee surgery at the International Society for Computer Assisted Orthopaedic Surgery (CAOS) annual meeting in Beijing, China earlier this month. The award-winning research demonstrated the potential for ExactechGPS to accurately manage soft tissue balance, bone cuts and overall alignment of the knee in joint replacement surgery.... Read more »
  • U of Florida and Penn Ink Licensing Deal for Gene Therapy to Treat Retinal Disease (Tech Transfer eNews Blog)
    Biotech company Ophthotech Corporation has entered into an exclusive global license agreement with the University of Florida Research Foundation (UFRF) and the University of Pennsylvania (Penn) to commercialize a treatment for a disease that causes blindness. The licensed technology is an adeno-associated virus (AAV) gene therapy to treat rhodopsin-mediated autosomal dominant retinitis pigmentosa (RHO-adRP), an orphan monogenic disease characterized by progressive and severe loss of vision leading to blindness. Proof-of-concept studies of the therapy have shown promising results in a canine disease model, and Ophthotech plans to launch a Phase 1/2 clinical trial in early 2020.... Read more »
  • Cannabix Technologies Provides Technology Update on Marijuana Breathalyzer Development (Globe Newswire)
    Cannabix Technologies Inc., a UF startup developing the Cannabix Marijuana Breathalyzer for law enforcement and the workplace, has reported that recent testing with Beta 3.0 has shown the identification and first order separation of two key metabolites of ∆9-tetrahydrocannabinol (“THC”), being 11-hydroxy-delta-9-tetrahydrocannabinol and 11-nor-9-carboxy-tetrahydrocannabinol in standards. In addition, scientists have made significant progress towards using lower flow rates that will become important for user groups with poor lung function. Furthermore, engineers have been testing a new breath capture method that can hold THC breath samples in a stable manner for several days. ∆9-tetrahydrocannabinol (“THC”) the main psychoactive component of marijuana is metabolized into 11-nor-9-carboxy-tetrahydrocannabinol at different rates based on route of entry into the body. Smoked THC is converted predominantly to 11-nor-9-carboxy-tetrahydrocannabinol which is then glucuronidated to a water-soluble form that can be detected in body fluids. Ingested THC is metabolized via the hepatic portal circulation to 11-hydroxy-delta-9-tetrahydrocannabinol prior to oxidation to 11-nor-9-carboxy-tetrahydrocannabinol. The Cannabix FAIMS device coupled to real time switchable mass spectrometry is actively being tuned to detect these key molecules and their complex pathways in the body to enable the identification of recency of use.... Read more »

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