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Welcome to the Rigorous Reproducible Responsible Research Integrity at UF (R4I@UF) website!  Please visit each month for a new case that may be used as a framework for a brief conversation about best research practices in your lab meeting, research conference, journal club, or any research meeting.


March 2025 Case of the Month: Data Management

Dr. W is a Principal Investigator leading a large research laboratory with several technicians, two postdoctoral fellows, three graduate students, and several undergraduate students. The entire group has been working on a project related to the relationship between hormones and obesity. They have isolated a key hormone in mice that is necessary to maintain normal weight, and have recently published a paper on this new finding, with Dr. W as the senior author. Two months after the paper has been published, Dr. W receives an inquiry from a researcher at another university who has had difficulty replicating some of the group’s work. The researcher requests to see the original data used to support a figure presented in the paper. Dr. W asks members of his team for the original data related to the figure and they report that the experiments that generated that data were conducted by Dr. V, a post-doctoral fellow who recently left the laboratory to take a position in another country. Dr. V had been told to leave the original data in the lab and to take copies. A search of the laboratory for the original data has been less than satisfactory. The group discovers that there are several problems with the data, including the lack of a bound notebook and the availability of some “post-it” sticky notes written in another language. They also have trouble retrieving data that were stored on the computer used by Dr. V, which has been infected by a virus.

  1. What are the data management issues can you identify in this scenario?
  2. How should Dr. W and the research team deal with each issue?
  3. Are there any data management practices in your research group that could be improved?
  4. Discuss briefly a plan to follow up on this conversation.

Please see the Resources link above for more information about Data Management Practices.


This scenario is adapted from Theme 5 – Data Management (2005) at https://oir.nih.gov/sourcebook/ethical-conduct/responsible-conduct-research-training/annual-review-ethics-case-studies/research-cases-use-nih-community


This website is a service of UF Research Integrity, Security & Compliance and the RCR on Campusworking group. We believe that research integrity is not achieved by simply taking an RCR course and “checking the box” that training is done. Our vision is to maintain a research culture in our everyday lives as UF researchers and research trainees in which we naturally follow best practices to ensure that the research we do is responsible, rigorous, and reproducible.

To submit a “Case of the Month” for the R4I@UF website, please contact Wayne T. McCormack, PhD (mccormac at ufl.edu).